HYL001

SKU: orb2665182

Description

HYL001 (compound 338) is a potent and selective ALK5 (TGFβ receptor 1) inhibitor. It demonstrates superior in vivo efficacy compared to galunisertib, effectively reducing liver metastases in mouse models. This small molecule is a valuable tool for researching TGFβ signaling in oncology, fibrosis, and immunology across in vitro and in vivo studies.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2426547-83-1
• MW: 342.39
• Formula: C₂₁H₁₈N₄O
• SMILES: OC=1C=CC2=NC=CC(=C2C1)C=3C(=NN4C3CCC4)C=5N=C(C=CC5)C
• Target: TGF-beta/Smad,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

151904182