Hydroxyprogesterone caproate

SKU: orb1300401

Description

Hydroxyprogesterone caproate is a synthetic progestin that acts as an agonist for nuclear progesterone receptors. It is widely used in research to study mechanisms of ovulation inhibition and endometrial modulation, with applications in reproductive biology and endocrinology for both in vitro and in vivo experimental models.

Research Area

Cell Biology

Key Properties

• CAS Number: 630-56-8
• MW: 428.60
• Purity: 99.78%
• Formula: C₂₇H₄₀O₄
• SMILES: CCCCCC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)=O
• Target: Autophagy,Others,Progesterone Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.67 mM);DMSO:50 mg/mL (116.66 mM);Ethanol:79 mg/mL (184.32 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• In Vivo:
  Hydroxyprogesterone caproate is administered to pregnant rats in order to assess the effect of intraperitoneal exposure to supranormal levels of hydroxyprogesterone caproate on the male reproductive potential in the first generation. The cauda epididymal sperm count and motility decrease significantly in rats exposed to hydroxyprogesterone caproate during embryonic development, when compared with control rats. The levels of serum testosterone decrease with an increase in follicle stimulating hormone and luteinizing hormone in adult rats exposed to hydroxyprogesterone caproate during the embryonic stage.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Primolut Depot, ULK2, ULK1, inhibit, Inhibitor, Hydroxyprogesterone caproate, Hydroxyprogesterone Caproate, Hormofort, 17alpha-Hydroxyprogesterone Caproate, 17alpha-Hydroxyprogesterone Hexanoate, 17α-Hydroxyprogesterone Caproate, 17α-Hydroxyprogesterone caproate, 17α-Hydroxyprogesterone Hexanoate, 17α-Hydroxyprogesterone hexanoate, 17a-Hydroxyprogesterone Caproate, 17a-Hydroxyprogesterone Hexanoate, Delalutin

Compound Identifiers

PubChem CID

169870