Hydroxymethyl dasatinib

SKU: orb2565989

Description

Hydroxymethyl dasatinib (M24) is a benzylhydroxy metabolite of the anticancer drug Dasatinib. It exhibits potent anti-proliferative activity in vitro, with an IC50 of 46.7 nM against K562 chronic myeloid leukemia cells, making it a relevant compound for oncology and kinase signaling research.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 910297-58-4
• MW: 504.01
• Purity: 98.98% (May vary between batches)
• Formula: C₂₂H₂₆ClN₇O₃S
• SMILES: O=C(NC=1C(Cl)=CC=CC1CO)C=2SC(=NC2)NC=3N=C(N=C(C3)N4CCN(CCO)CC4)C
• Target: Bcr-Abl

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11854534