Hydroxygenkwanin

SKU: orb1222538

Description

Hydroxygenkwanin possesses significant the antioxidative activity . Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin and Hydroxygenkwanin may be a promising method for glioma chemotherapy.

Key Properties

• CAS Number: 20243-59-8
• MW: 300.26
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₂O₆
• SMILES: COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O
• Target: Antioxidant
• Solubility: In Vitro: DMSO : 10 mg/mL (33.30 mM)

Bioactivity

• In Vitro:
  Hydroxygenkwanin (7-O-Methylluteolin) inhibits C6 glioma cell proliferation in a dose dependent manner. Hydroxygenkwanin induces the cell cycle arrest by flow cytometry and inhibits colony formation ability and cell movement. Hydroxygenkwanin induces cell cycle arrest through p21 activation and causes intrinsic cell apoptosis pathway.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Antioxidant