Hydrangenol

SKU: orb1297101

Description

Hydrangenol, a natural compound isolated from Hydrangea serrata, exhibits oral anti-photoaging activity. Research indicates it reduces MMP and inflammatory cytokine expression while increasing moisturizing factors and antioxidant genes in models, thereby helping to prevent wrinkle formation.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 480-47-7
• MW: 256.25
• Purity: 99.88% (May vary between batches)
• Formula: C₁₅H₁₂O₄
• SMILES: O=C1C=2C(CC(O1)C3=CC=C(O)C=C3)=CC=CC2O
• Target: Autophagy,Antifection,NO Synthase,ERK,p38 MAPK,NF-κB,NOS,Interleukin,Nrf2,MMP,COX
• Solubility: DMSO:60 mg/mL (234.15 mM)

Bioactivity

• In Vitro:
  Hydrangenol increased the expression of involucrin, filaggrin, and aquaporin-3 (AQP3) as well as hyaluronic acid (HA) production via hyaluronidase (HYAL)-1/-2 downregulation. Consistent with the recovery of collagen composition, the expression of Pro-COL1A1 was increased by hydrangenol.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Nrf2, NOSynthase, NOS, NF-κB, NFκB, NF-kB, NFkB, NO Synthase, NO, HO-1, Hydrangenol, (HO)-1, Antifection

Compound Identifiers

PubChem CID

119199