HXR9

SKU: orb1690147

Description

HXR9 is a cell-permeable peptide antagonist that disrupts the HOX/PBX interaction, specifically for paralogue groups 1-8. It selectively inhibits proliferation and induces apoptosis in cells with high HOXA/PBX3 expression, such as MLL-rearranged leukemia cells, making it a valuable tool for studying oncogenic transcription factor complexes in cancer research.

Research Area

Cell Biology

Key Properties

• Target: Apoptosis
• CAS Number: 917953-08-3
• MW: 2718.26
• Formula: C₁₁₉H₁₉₃N₅₃O₂₀S
• SMILES: CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168013268