HVH-2930

SKU: orb2646202

Description

HVH-2930 is a potent HSP90 inhibitor that reduces viability in both trastuzumab-sensitive and -resistant breast cancer cell lines by degrading key client proteins like HER2 and AKT. It demonstrates significant in vivo antitumor activity and favorable pharmacokinetics, supporting its use in oncology research for studying HSP90-dependent pathways and therapeutic resistance.

Research Area

Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 3034605-72-3
• MW: 488.62
• Formula: C₂₉H₃₆N₄O₃
• SMILES: O=C(NC=1C=CC=2C(=NN(C2C1)CCC3CCN(C)CC3)C)C4=CC=C5OC(C=CC5=C4OC)(C)C
• Target: Survivin,Akt,HSP,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171514416