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Catalog Number | orb2692737 |
---|---|
Category | Proteins |
Description | Humanin, an anti-apoptotic peptide of 24 amino acids, is a Bax inhibitor. Humanin prevents the translocation of Bax from cytosol to mitochondria, blocks Bax from the inactive to active conformation. Humanin is a mitochondria-associated peptide with a neuroprotective effect against AD-related neurotoxicity. Humanin also improves overall insulin sensitivity in animal. Humanin are related to aging. Humanin analogue, in which the serine at position 14 is replaced by glycine, names HNG. |
Target | others |
Purity | ≥95% |
Protein Sequence | {Met}-APRGFSCLLLLTSEIDLPVKRRA |
MW | 2687.28 |
Solubility (25°C) | Water: 100 mg/mL |
Formula | C119H204N34O32S2 |
Note | For research use only |
Greater than 95% as determined by SDS-PAGE. | |
29.3 kDa | |
E.coli |
Greater than 85% as determined by SDS-PAGE. | |
29.4 kDa | |
E.coli |
Greater than 85% as determined by SDS-PAGE. | |
31.6 kDa | |
Mammalian cell |