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| Catalog Number | orb257866 |
|---|---|
| Category | Proteins |
| Description | Human TGFBR2, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Asp 159 (Accession # NP_003233). |
| Reactivity | Human |
| Tag | C-Fc |
| Form/Appearance | Powder |
| Purity | 95% |
| Conjugation | Unconjugated |
| MW | 42.1 kDa |
| Target | TGF-beta RII, TGFBR2 |
| UniProt ID | P37173 |
| Protein Sequence | NP_003233 |
| Source | Human TGFBR2, Fc Tag (orb257866) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Asp 159 (Accession # NP_003233). |
| Expression System | HEK293 |
| Biological Origin | Human |
| Expression Region | Thr 23 - Asp 159 |
| Endotoxins | 1.0 EU per μg |
| NCBI | NP_003233 |
| Storage | -20℃ |
| Buffer/Preservatives | Tris with Glycine, Arginine and NaCl, pH7.5 |
| Alternative names | TGFBR2,TGFR2,TbetaR-II,TGFβR2 Read more... |
| Note | For research use only |
| Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42.1 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Expiration Date | 6 months from date of receipt. |
Zhang, Sen et al. Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling Am J Transl Res, 9, 115-125 (2017)
SDS-PAGE analysis of Human TGF-beta RII protein
