Human SOST Protein, His Tag

SKU: orb257550

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Description

Human SOST, His Tag is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Tyr 213 (Accession # AAI01087.1).

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 22.3 kDa. The protein migrates as 30-34 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to different glycosylation.

Key Properties

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Expression System	HEK293
Target	SOST
Reactivity	Human
Tag	N-6×His
Molecular Weight	22.3 kDa
Expression Region	Gln 24 - Tyr 213
Purity	90%
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
Form/Appearance	Powder
Buffer/Preservatives	PBS, pH 7.4
Disclaimer	For research use only

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SDS-PAGE analysis of Human SOST protein

Quick Database Links

Gene Symbol

SOST

UniProt

AAI01087.1

UniProt Details

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No UniProt data available

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Protocol Information

Find More Protocols

Wu, Y. et al. Upregulated serum sclerostin level in the T2DM patients with femur fracture inhibits the expression of bone formation/remodeling-associated biomarkers via antagonizing Wnt signaling Eur Rev Med Pharmacol Sci, 21, 470-478 (2017)

PubMed: 28239825