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Catalog Number | orb257833 |
---|---|
Category | Proteins |
Description | Serpin A3 is also known as Alpha-1-antichymotrypsin (ACT or AACT), Cell growth-inhibiting gene 24/25 protein, which belongs to the serpin family. Serpin A3 can bind D. Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. |
Reactivity | Human |
Tag | C-10×His |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 46.6 kDa |
Target | Serpin A3 |
UniProt ID | P01011 |
Protein Sequence | AAH03559 |
Source | Human Serpin A3, His Tag (orb257833) is expressed from human 293 cells (HEK293). It contains AA His 24 - Ala 423 (Accession # AAH03559). |
Expression System | HEK293 |
Biological Origin | Human |
Expression Region | His 24 - Ala 423 |
Endotoxins | 1.0 EU per μg |
NCBI | AAH03559 |
Storage | -20°C |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | SERPINA3,ACT,AACT,GIG24,GIG25 Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.6 kDa. The protein migrates as 50-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human Serpin A3 protein
ELISA, MS, SDS-PAGE, WB | |
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. | |
Human cells |
> 97% by SDS-PAGE. | |
Recombinant Human Serpin A3/AACT Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asn26-Ala423) of human Serpin A3/AACT (Accession #NP_001076.2) fused with a 6��His Tag at the C-terminus. |