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Human SCF Protein, His Tag

Catalog Number: orb1743048

Select Product Size
SizePriceQuantity
100 μg$ 750.00
1 mg$ 4,090.00
100 μg Enquire
1 mg Enquire
DispatchUsually dispatched within 5-10 working days
Catalog Numberorb1743048
CategoryProteins
DescriptionStem Cell Factor is also known as SCF, kit-ligand, KL, steel factor, KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, or SHEP7, and is a cytokine that binds to the c-Kit receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis (formation of blood cells), spermatogenesis, and melanogenesis. The soluble and transmembrane forms of the protein are formed by alternative splicing of the same R transcript.Soluble and transmembrane SCF is produced by fibroblasts and endothelial cells. Soluble SCF has a molecular weight of 18, 5 KDa and forms a dimer. SCF plays an important role in the hematopoiesis during embryonic development. Sites where hematopoiesis takes place, such as the fetal liver and bone marrow, all express SCF. During development, the presence of the SCF also plays an important role in the localization of melanocytes, cells that produce melanin and control pigmentation. SCF plays a role in the regulation of HSCs in the stem cell niche in the bone marrow. SCF may be used along with other cytokines to culture HSCs and hematopoietic progenitors. The expansion of these cells ex-vivo (outside the body) would allow advances in bone-marrow transplantation, in which HSCs are transferred to a patient to re-establish blood formation.
TargetSCF
ConjugationUnconjugated
TagC-10×His
ReactivityHuman
Form/AppearancePowder
Buffer/PreservativesPBS, pH 7.4
Purity90%
UniProt IDP21583
MW20.3 kDa
Application notesThis protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.3 kDa. The protein migrates as 30-35 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression SystemHEK293
Endotoxins1.0 EU per μg
Biological OriginHuman
Biological ActivityImmobilized Human SCF, His Tag at 2 µg/mL (100 µL/well) can bind Human CD117, Fc Tag with a linear range of 0.5-8 ng/mL (QC tested).
Expression RegionGlu 26 - Ala 189
Storage-20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
Research AreaImmunology & Inflammation
NoteFor research use only
Expiration Date6 months from date of receipt.
Human SCF Protein, His Tag

Immobilized Human SCF, His Tag (Cat. No. orb1743048) at 2 μg/mL (100 μL/well) can bind Human CD117, Fc Tag (Cat. No. orb334886) with a linear range of 0.5-8 ng/mL (QC tested).

  • Mouse SCF Protein, His Tag [orb257825]

    Unconjugated

    95%

    19.5 kDa

    50 μg, 20 μg, 1 mg
  • Human SCF Protein, His Tag [orb2950097]

    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

    The protein has a predicted molecular mass of 22.4.0 kDa after removal of the signal peptide.

    100 μg, 50 μg, 10 μg
  • Recombinant Human SCF/C-kit ligand Protein, His Tag [orb1551343]

    > 97% by SDS-PAGE.

    Recombinant Human SCF/C-kit ligand Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Glu26-His Tag214) of human SCF/C-kit ligand (Accession #NP_000890.1) fused with a 6��His Tag at the C-terminus.

    100 μg, 50 μg
  • Human Kit ligand Protein [orb1475799]

    50 μg, 500 μg
  • FBXO44 Protein, Human, Recombinant (His & Myc) [orb1978589]

    37.2 kDa (predicted)

    1 mg, 100 μg, 20 μg