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Catalog Number | orb257753 |
---|---|
Category | Proteins |
Description | Human PD-1 Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Gln 167 (Accession # NP_005009.2). |
Reactivity | Human |
Tag | C-Fc |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 42.1 kDa |
Target | PD-1, PDCD1 |
UniProt ID | Q15116 |
Protein Sequence | NP_005009.2 |
Source | Human PD-1, Fc Tag, low endotoxin (orb257753) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Gln 167 (Accession # NP_005009.2). |
Expression System | HEK293 |
Biological Origin | Human |
Expression Region | Leu 25 - Gln 167 |
Endotoxins | 0.1 EU per μg |
NCBI | NP_005009.2 |
Storage | -20℃ |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | PDCD1,PD1,CD279,SLEB2 Read more... |
Note | For research use only |
Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42.1 kDa. The protein migrates as 56-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
Lai, Wei-Yun et al. A Novel PD-L1-targeting Antagonistic DNA Aptamer With Antitumor Effects Mol Ther Nucleic Acids, 5, e397 (2016)
SDS-PAGE analysis of Human PD-1 protein
Line graph illustrates about the sensitivity range of Human PD-1 protein using different concentrations
The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 42.9 kDa after removal of the signal peptide. | |
Mammalian |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 43.5 kDa after removal of the signal peptide. | |
Mammalian |
Unconjugated | |
90% | |
42.6 kDa | |
Cynomolgus PD-1, Fc Tag (orb257749) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Gln 167 (Accession # B0LAJ3). |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 42.3 kDa after removal of the signal peptide. The apparent molecular mass of mPD-1-hFc is approximately 35-70 kDa due to glycosylation. | |
Mammalian |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 42.3 kDa after removal of the signal peptide. The apparent molecular mass of dPD-1-hFc is approximately 55-70 kDa due to glycosylation. | |
Mammalian |