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Catalog Number | orb1806487 |
---|---|
Category | Proteins |
Description | IGFBP6 (Insulin-like Growth Factor Binding Protein 6) is a member of the insulin-like growth factor binding protein (IGFBP) family. Like other IGFBPs, IGFBP6 can bind to insulin-like growth factors (IGFs) and modulate their activity and distribution in the body. IGFBP6 is an important regulator of the IGF signaling pathway. It modulates the activity and availability of IGFs, impacting cellular processes and playing a role in development and disease. |
Reactivity | Human |
Tag | C-10×His |
Form/Appearance | Powder |
Purity | 90% |
Conjugation | Unconjugated |
MW | 24.5 kDa |
Target | IGFBP-6 |
UniProt ID | P24592 |
Source | Human IGFBP-6 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Arg 28 - Gly 240 (Accession # P24592). |
Expression System | HEK293 |
Expression Region | Arg 28 - Gly 240 |
Endotoxins | 1.0 EU per μg |
Storage | -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Buffer/Preservatives | PBS, pH 7.4 |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.5 kDa. The protein migrates as 30-38 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
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