Human IGFBP-2 Protein, His Tag (MALS verified)

• Catalog Number: orb1806488
• Category: Proteins
• Description: The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 33.3 kDa
• Target: IGFBP-2
• UniProt ID: P18065
• Source: Human IGFBP-2 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 36 - Gln325 (Accession # P18065).
• Expression System: HEK293
• Biological Activity: Immobilized Human IGF-I, Fc Tag at 5 μg/mL (100 μL/well) can bind Human IGFBP-2 Protein, His Tag with a linear range of 10-156 ng/mL (QC tested).
• Expression Region: Ala 36 - Gln325
• Endotoxins: 1.0 EU per μg
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, pH 7.4
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.3 kDa. The protein migrates as 33-35 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

Immobilized Human IGF-I, Fc Tag (Cat. No. orb257564) at 5 μg/mL (100 μL/well) can bind Human IGFBP-2 Protein, His Tag (Cat. No. orb1806488) with a linear range of 10-156 ng/mL (QC tested).