Human FGF-5 Protein, His Tag

SKU: orb1818948

Description

Fibroblast growth factor-5 (FGF5) is a member of the fibroblast growth factor (FGF) family and acts as a crucial regulator of hair growth and an oncogenic factor in several human cancers. Generally, Fibroblast growth factor 5 (FGF5) is widely expressed in embryonic but scarcely in adult tissues. Overexpression of FGF5 has been associated with prostate cancer, pancreatic cancer, breast cancer, renal cell carcinoma, etc

Images & Validation

• Application Notes:
  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.4 kDa. The protein migrates as 35-38 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Key Properties

• Expression System: E. coli
• Target: FGF-5
• Reactivity: Human
• Tag: C-10×His
• Molecular Weight: 29.4 kDa
• Expression Region: AA Glu 23 - Gly 268
• Purity: 90%
• Endotoxins: 1.0 EU per μg
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
• Form/Appearance: Powder
• Buffer/Preservatives: PBS, pH 7.4
• Disclaimer: For research use only

Human FGF-5 Protein, His Tag captured on CM5 chip via anti-His antibody can bind Human FGF R2, Fc Tag with an affinity constant of 63.3 nM as determined in a SPR assay.

Human FGF-5 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%

Quick Database Links

Gene Symbol

FGF-5

UniProt

P12034