Human FGF-4 Protein, His Tag

• Catalog Number: orb1733261
• Category: Proteins
• Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008]
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 19.8 kDa
• Target: FGF-4
• Source: Human FGF-4 Protein, His Tag (orb1733261) is expressed from E. coli cells. It contains AA Ser 54 - Leu 206 (Accession # P08620-1).
• Expression System: E. coli
• Expression Region: Ser 54 - Leu 206
• Endotoxins: 1.0 EU per μg
• Storage: -20°C
• Buffer/Preservatives: MOPS, Na2SO4, Arginine and EDTA
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.8 kDa. The protein migrates as 23-24 kDa under reducing (R) condition (SDS-PAGE).
• Expiration Date: 6 months from date of receipt.