Human Fc Receptor Blocking Solution Protein, Tag Free

SKU: orb3158143

Description

Fc receptors expressed on the surface of immune cells such as monocytes, macrophages, dendritic cells, and certain lymphocyte subsets can bind to the Fc region of antibodies in a non‑antigen‑specific manner. This Fc–Fc receptor interaction often leads to high background signals in flow cytometry, immunofluorescence, and other immunoassays, complicating the interpretation of true antigen‑specific binding. To address this, Fc receptor blocking reagents are used prior to antibody staining to occupy Fc receptors, thereby preventing non‑specific binding and improving assay specificity and signal‑to‑noise ratio. The blocking efficiency may vary depending on the antibody isotype, Fc receptor subtype, and cell type tested.

Images & Validation

• Application Notes:
  This protein carries no "tag". The protein has a calculated MW of 31.2 kDa.

Key Properties

• Expression System: HEK293
• Target: Fc Receptor Blocking Solution
• Reactivity: Human
• Tag: Native
• Endotoxins: 1.0 EU per μg
• Conjugation: Unconjugated
• MW: 31.2 kDa

Storage & Handling

• Storage: -70°C
• Form/Appearance: Liquid
• Buffer/Preservatives: PBS, pH 7.4
• Expiration Date: 6 months from date of receipt.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Fc Receptor Blocking Solution