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Human DKK-1 Protein

SKU: orb3148587

Description

Human DKK-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of DKK-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Human DKK-1 inhibition is critical for bone formation and homeostasis. In addition, Human DKK-1 can act as either a tumor suppressor or promoter of metastasis.

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

Storage & Handling

StorageLyophilized Human DKK-1 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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Available Sizes

Select a size below

10 μg
$ 170.00
50 μg
$ 320.00
500 μg
$ 1,230.00