Human CLEC4C Protein, His Tag

• Catalog Number: orb1149293
• Category: Proteins
• Description: CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)Glcc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
• Reactivity: Human
• Tag: N-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 26.6 kDa
• Target: CLEC4C, BDCA2
• UniProt ID: Q8WTT0
• Protein Sequence: NP_569708.1
• Source: Human CLEC4C, His Tag (orb1149293) is expressed from human 293 cells (HEK293). It contains AA Asn 45 - Ile 213 (Accession # Q8WTT0-1).
• Expression System: HEK293
• Biological Origin: Human
• Expression Region: Asn 45 - Ile 213
• Endotoxins: 1.0 EU per μg
• NCBI: NP_569708.1
• Storage: -20°C
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: DLEC,CLEC4C,BDCA-2,CD303,CLECSF11,CLECSF7, HECL
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 26.6 kDa. The protein migrates as 33-40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.