Human BMP-4 / BMP2B Protein, Research Grade

SKU: orb3158105

Description

Bone Morphogenetic Protein 4 (BMP4) is a member of growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. BMP-4 Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. BMP-4 can acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.

Research Area

Stem Cell & Developmental Biology

Images & Validation

• Application Notes:
  This protein carries no "tag". The protein has a calculated MW of 13.1 kDa. The protein migrates as 21 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

• Expression System: CHO
• Target: BMP-4
• Reactivity: Human
• Tag: Native
• Molecular Weight: 13.1 kDa
• Expression Region: Ser 293 - Arg 408
• Purity: 95%
• Endotoxins: 0.01 EU per μg
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C
• Form/Appearance: Powder
• Buffer/Preservatives: 20 mM Citric acid, pH 2.2
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

BMP-4

RefSeq (Protein):NP_001193.2