Human ACE2 Ready-To-Use IHC Kit

• Catalog Number: orb1817144
• Category: Assays and Kits
• Description: orb1817144 is a ready-to-use IHC kit for staining of human ACE2. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data. Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin. ACE2 has direct effects on cardiac function,a and is expressed predominantly in vascular endothelial cells of the heart and the kidneys. ACE2 is not sensitive to the ACE inhibitor drugs used to treat hypertension. ACE2 receptors have been shown to be the entry point into human cells for some coronaviruses, including the SARS virus. A number of studies have identified that the entry point is the same for SARS-CoV-2, the COVID-19 virus.
• Reactivity: Human
• Storage: Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
• Note: For research use only
• Sample Types: FFPE tissue
• Expiration Date: Please enquire.