HTS07545

SKU: orb1688721

Description

HTS07545 is a potent and selective sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC50 of 30 nM, effectively modulating cellular hydrogen sulfide metabolism. It has been utilized in research models, including in vitro enzymatic assays and in vivo studies relevant to heart failure pathophysiology, to investigate the role of H2S signaling.

Research Area

Metabolism Research

Key Properties

• CAS Number: 118666-03-8
• MW: 358.39
• Purity: 99.71% (May vary between batches)
• Formula: C₂₂H₁₈N₂O₃
• SMILES: C(#N)C=1C(=CC(=NC1OCC(OCC)=O)C2=CC=CC=C2)C3=CC=CC=C3
• Target: Mitochondrial Metabolism,NADPH,Others
• Solubility: DMSO:90 mg/mL (251.12 mM)

Bioactivity

• Target IC50:
  SQOR:30 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NQO

Compound Identifiers

PubChem CID

2813721