HTR2A antagonist 1

SKU: orb2945124

Description

This potent HTR2A antagonist (IC50 = 42.79 nM) triggers apoptosis and sub-G1 arrest in colorectal cancer cells via p53/p21/caspase-3 activation. Its good metabolic stability supports its utility in both in vitro and in vivo research models for studying colorectal cancer pathways.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• MW: 706.65
• Formula: C₃₅H₄₃Cl₂F₂N₅O₄
• SMILES: C1CNCCC1N(CC2=CC=C(C=C2)F)C(=O)NCC3=CC=C(C=C3)OCC(CN4CCC(CC4)C5=NOC6=C5C=CC(=C6)F)O.Cl.Cl
• Target: 5-HT Receptor,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676827