HTH-01-091 TFA

SKU: orb1983394

Description

HTH-01-091 (TFA) is a potent, selective MELK inhibitor (IC50 = 10.5 nM) with additional activity against kinases including PIM1/2/3 and RIPK2. Its profile supports its use as a chemical probe in breast cancer research, facilitating studies on tumor cell proliferation and survival in both cellular and animal models.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• MW: 613.46
• Formula: C₂₈H₂₉Cl₂F₃N₄O₄
• Target: Others,RIP kinase,Pim,GSK-3,DYRK,MELK,CDK,mTOR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others,RIP kinase,Pim,GSK-3,DYRK,MELK,CDK,mTOR