HSP90/mTOR-IN-1

SKU: orb1744672

Description

HSP90/mTOR-IN-1 is a potent, orally bioavailable dual inhibitor of Hsp90 (IC50=69 nM) and mTOR (IC50=29 nM). It demonstrates anti-proliferative effects in SW780 bladder cancer cells by inducing apoptosis and autophagy and shows significant in vivo anti-tumor activity, making it a valuable tool for oncology research.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• MW: 717.21
• Formula: C₃₆H₃₄ClFN₆O₅S
• SMILES: CC(C)C1=CC(=C(C=C1O)O)C(=O)N2CCC3=C(C2)SC4=NC(=NC(=C34)N5CCOCC5)C6=CC=C(C=C6)NC(=O)NC7=CC(=C(C=C7)F)Cl
• Target: HSP,Apoptosis,Autophagy,Others,mTOR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164887596