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Hsp90-IN-47

SKU: orb3210603

Description

Hsp90-IN-47 (Compound C15) is an Hsp90 inhibitor and antifungal agent with an IC50 of 0.014 μM for Hsp90α. When combined with Fluconazole, Hsp90-IN-47 demonstrates significant synergistic antifungal effects against the Fluconazole-resistant strain Candida albicans 0304103. Additionally, Hsp90-IN-47 exhibits antitumor activity against acute myeloid leukemia and non-small cell lung cancer.

Images & Validation

Key Properties

CAS Number958888-13-6
MW326.35
FormulaC17H18N4O3
SMILESO=C1NN=C(C=2C=C(C(O)=CC2O)C(C)C)N1C3=CC=C(N)C=C3
TargetHSP,Antifungal

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information