Hsp90-IN-34

SKU: orb2802535

Description

Hsp90-IN-34 (HAM-1) is a potent, selective inhibitor of the Aha1-Hsp90 protein-protein interaction, exhibiting a KDapp of 23.5 µM. By disrupting this co-chaperone complex, it modulates Hsp90 ATPase activity and serves as a valuable chemical probe for studying Hsp90 function in cancer and neurodegenerative disease research, both in vitro and in cellular models.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 439588-33-7
• MW: 416.38
• Formula: C₂₂H₁₄F₂N₆O
• SMILES: N#CC1=C(OC=2NN=C(C=3C=CC(F)=CC3)C2C1C4=CNN=C4C=5C=CC(F)=CC5)N
• Target: HSP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

3942747