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HSP70/SIRT2-IN-2

SKU: orb1942599

Description

HSP70/SIRT2-IN-2 (1a) is a dual-target inhibitor of SIRT2 and HSP70, showing SIRT2 inhibitory activity with an IC50 of 45.1±5.0 µM. This compound exhibits antitumor properties and serves as a useful chemical probe for researching cancer biology and protein deacetylation mechanisms in cellular models.

Research Area

Cell Biology, Epigenetics & Chromatin, Metabolism Research, Molecular Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1796557-72-6
MW355.5
FormulaC17H13N3S3
SMILESN1=C(SC=C1C2=NC=3C=CC=CC3S2)NC=4C=CC=C(SC)C4
TargetSirtuin,HSP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information