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HSN748

HSN748

Catalog Number: orb2945692

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Product Properties
Catalog Numberorb2945692
CategorySmall Molecules
DescriptionHSN748 is an analog of ponatinib and acts as a multi-kinase inhibitor. It exhibits inhibitory activity against kinases such as FLT3, ABL1, RET, PDGFRα/β, MNK1, and MNK2. HSN748 can suppress the growth of chronic myeloid leukemia and acute myeloid leukemia cell lines, making it a useful compound in leukemia research.
Targetc-RET,Bcr-Abl,PDGFR,FLT,MNK
MW519.521
CAS Number2409925-53-5
FormulaC27H24F3N7O
SMILESO=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCN(C)CC2)C=3C=NC=C(C#CC4=CN=C5C=CC=NN45)C3
Storage-20°C
Research AreaCardiovascular Research, Cell Biology, Signal Tran
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NoteFor research use only
Expiration Date12 months from date of receipt.
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