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| Catalog Number | orb2945692 |
|---|---|
| Category | Small Molecules |
| Description | HSN748 is an analog of ponatinib and acts as a multi-kinase inhibitor. It exhibits inhibitory activity against kinases such as FLT3, ABL1, RET, PDGFRα/β, MNK1, and MNK2. HSN748 can suppress the growth of chronic myeloid leukemia and acute myeloid leukemia cell lines, making it a useful compound in leukemia research. |
| Target | c-RET,Bcr-Abl,PDGFR,FLT,MNK |
| MW | 519.521 |
| CAS Number | 2409925-53-5 |
| Formula | C27H24F3N7O |
| SMILES | O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCN(C)CC2)C=3C=NC=C(C#CC4=CN=C5C=CC=NN45)C3 |
| Storage | -20°C |
| Research Area | Cardiovascular Research, Cell Biology, Signal Tran Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)