HSD17B13-IN-35

SKU: orb2566060

Description

HSD17B13-IN-35 (compound 76) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 < 0.1 µM. It serves as a key research tool for investigating the role of HSD17B13 in liver lipid metabolism and is relevant for studies on nonalcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2770246-69-8
• MW: 524.33
• Formula: C₂₅H₁₆Cl₂FN₅O₃
• SMILES: N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=NN(C=C4)C5=C(F)C=CC=C5)C3=O)=CC=C2
• Target: Dehydrogenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163301215