HSD17B13-IN-104

SKU: orb3135590

Description

HSD17B13-IN-104 (Compound 32) is an orally active and potent inhibitor of HSD17B13 with high selectivity (IC50=2.5 nM). It modulates liver lipid metabolism by inhibiting the SREBP-1c/FAS pathway and blocks the enzymatic activity of HSD17B13 to alleviate hepatic lipid accumulation. HSD17B13-IN-104 shows potential for research in metabolic dysfunction-associated fatty liver disease.

Research Area

Metabolism Research

Key Properties

• CAS Number: 3075100-76-1
• MW: 454.89
• Formula: C₂₁H₁₈ClF₃N₂O₂S
• SMILES: O=C(C=1SC(=NC1C)C=2C=C(F)C(F)=C(O)C2F)N(CC3=CC=C(Cl)C=C3)C(C)C
• Target: Dehydrogenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Dehydrogenase