HPK1-IN-49

SKU: orb2663917

Description

HPK1-IN-49 (Compound I-4) is a small molecule inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) with an IC50 >100 nM. This compound is a useful research tool for investigating HPK1 function in immune cell signaling and T-cell activation in both in vitro and in vivo experimental contexts.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2845144-97-8
• MW: 500.57
• Formula: C₂₈H₂₉FN₆O₂
• SMILES: N(C1=C2C(=C(C=N1)C=3N4C(=NC3)C=C(F)C=C4)CNC2=O)C5=CC=C(C=C5)N6C[C@@H]([C@@](C)(C)O)CCC6

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165400296