HPK1-IN-2 dihydrochloride

SKU: orb2283517

Description

HPK1-IN-2 dihydrochloride is a potent, orally bioavailable small molecule inhibitor of HPK1 (IC50 <0.05 µM) with additional activity against Lck and Flt3 kinases. This compound has demonstrated significant antitumor efficacy in research models, supporting its investigation in oncology and immunology for both in vitro and in vivo studies.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2375595-72-3
• MW: 453.39
• Formula: C₁₉H₂₂Cl₂N₆OS
• SMILES: NC1=C(C=2NC=3C(N2)=CC=C(C3)N4CCN(C)CC4)C(=O)NC5=C1C=CS5.Cl
• Target: Others,Src,FLT,MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652982