HPK1-IN-10

SKU: orb1686379

Description

HPK1-IN-10 is a potent and selective small molecule inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1/MAP4K1), a key negative regulator of T-cell signaling. This compound is a valuable research tool for investigating HPK1 biology in immuno-oncology, enabling mechanistic studies in both cellular assays and in vivo disease models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2734168-69-3
• MW: 522.64
• Formula: C₃₁H₃₄N₆O₂
• SMILES: C(=O)(C1=CC=C(C=2C=3C(NC2)=NC=C(C3)C=4C=C5C(=CC4)N6C(CO5)CN(C)CC6)C=C1)N7CC(N(C)C)C7
• Target: Others,MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162679274