HPI-1 (hydrate)

SKU: orb1694530

Description

HPI-1 hydrate is a selective Hedgehog pathway inhibitor (IC50=1.5 μM) that acts downstream of Smoothened, blocking Gli-mediated signaling and proliferation. It is used in vitro and in vivo to study Hh-driven processes, including cancer and developmental biology research, without affecting Wnt signaling at relevant concentrations.

Key Properties

• CAS Number: 1262770-72-8
• MW: 481.54
• Formula: C₂₇H₃₁NO₇
• SMILES: O=C(OCCOC)C1=C(NC2=C(C(=O)CC(C=3C=CC=CC3OC)C2)C1C=4C=CC=C(O)C4)C.O
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71311904