HP590

SKU: orb1685857

Description

HP590 is a potent, orally bioavailable STAT3 inhibitor with IC50 values of 27.8 nM in a luciferase assay and 24.7 nM in an ATP inhibition assay. It demonstrates anti-proliferative and pro-apoptotic activity in gastric cancer cell lines, making it a valuable tool for oncology research targeting the STAT3 signaling pathway.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2971855-37-3
• MW: 590.52
• Formula: C₂₉H₂₄F₆N₄O₃
• SMILES: O=C(N1CCN(CC2=CC=C(OCC(F)(F)F)C=C2)CC1)C3=CC=C(C4=NC(C5=CC=C(C(F)(F)F)C=C5)=NO4)C=C3
• Target: Others,Apoptosis,STAT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165413048