Homobutein

SKU: orb1297102

Description

Homobutein

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 34000-39-0
• MW: 286.28
• Purity: 99.50% (May vary between batches)
• Formula: C₁₆H₁₄O₅
• SMILES: C(=C/C(=O)C1=C(O)C=C(O)C=C1)\C2=CC(OC)=C(O)C=C2
• Target: NF-κB|||Antioxidant|||HDAC|||Immunology/Inflammation related|||Parasite
• Solubility: H2O:< 1mg/mL (insoluble);DMSO:100 mg/mL (349.31 mM)

Bioactivity

• In Vitro:
  Homobutein (1 μg/mL) inhibits the growth of Toxoplasma gondii by 19.48% with IC50s of 15.0 and 16.1 µM for W2 and D6 strains of P. falciparum. Homobutein (20 - 40 μM) inhibits the viability and TNFα-induced NF-κB activity of K562 cells.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antioxidant, 3-O-Methylbutein, 2',4,4'-Trihydroxy-3-methoxychalcone, NF-κB, NFkB, NFκB, NF-kB, P. falciparum, iron chelator, inflammation, Inflammationrelated, Inflammation related, Immunology related, Immunologyrelated, Homobutein, HDAC

Compound Identifiers

PubChem CID

6438092