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Homo-VK-II-36

SKU: orb1298547

Description

Homo-VK-II-36 is a carvedilol analog functioning as a selective inhibitor of the RyR2 channel, thereby suppressing store-overload-induced calcium release (SOICR). This small molecule is utilized in cardiovascular research to investigate calcium signaling mechanisms in vitro and its role in conditions like catecholaminergic polymorphic ventricular tachycardia (CPVT).

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1479049-35-8
MW460.52
Purity99.26% (May vary between batches)
FormulaC27H28N2O5
SMILESCOc1ccccc1OCCN1CC(CCOc2cccc3[nH]c4ccccc4c23)OCC1=O
TargetCalcium Channel,Others
SolubilityDMSO:4.61 mg/mL (10.01 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Homo-V-II-36, HomoVKII36, Homo-VK-II-36, Homo VK II 36, RyR2 channel

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Key Properties

No computed properties available.

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Protocol Information

Homo-VK-II-36 (orb1298547)

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Available Sizes

Select a size below

1 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 210.00
5 mg
$ 210.00
10 mg
$ 310.00
25 mg
$ 500.00
50 mg
$ 710.00
100 mg
$ 1,000.00
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