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HL389-NHC2-PEG3-C2NH

SKU: orb3134617

Description

HL389-NHC2-PEG3-C2NH is capable of inhibiting the proliferation of cancer cells MDA-MB-231 and MCF-7, with IC50 values of 11.39 μM and 9.66 μM, respectively. It serves as a conjugate of an E3 ligase ligand and linker, employed in the synthesis of the PROTAC degrader HL435.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

FormulaC28H33BrF3N3O6
TargetE3 Ligase Ligand-Linker Conjugates

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information