HJ03

SKU: orb3211341

Description

HJ03 is an orally bioavailable inducer of DNA damage and ferroptosis (ferroptosis) that can cross the blood-brain barrier. It triggers ferroptosis by enhancing intracellular ROS, Fe2+ accumulation, and lipid peroxidation. HJ03 induces DNA adducts and interstrand crosslinks, hindering DNA replication and transcription, leading to G2/M phase arrest and cell apoptosis (apoptosis). It is applicable for research on glioblastoma multiforme and colorectal cancer.

Key Properties

• CAS Number: 3028123-48-7
• MW: 482.75
• Formula: C₁₆H₂₂Cl₃N₇O₄
• SMILES: O=NN(C(=O)NCCCl)CCN(C=1C=CC=C(Cl)C1)CCN(N=O)C(=O)NCCCl
• Target: Ferroptosis,DNA Alkylator/Crosslinker,ROS,Apoptosis,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Ferroptosis,DNA Alkylator/Crosslinker,ROS,Apoptosis,DNA/RNA Synthesis