HJ-4

SKU: orb3173398

Description

HJ-4 is a derivative of Piperine. It effectively inhibits the proliferation of colorectal cancer (CRC) cells by reducing colony formation and DNA synthesis in a dose-dependent manner. HJ-4 notably impairs the adhesion, migration, and invasion of CRC cells and induces apoptosis. In a chicken embryo chorioallantoic membrane (CAM) model with implanted HCT116/SW480 tumor spheroids, HJ-4 demonstrates antitumor efficacy. HJ-4 is applicable for colorectal cancer (CRC) research.

Research Area

Cell Biology

Key Properties

• CAS Number: 1313741-00-2
• MW: 392.46
• Formula: C₂₃H₂₄N₂O₄
• SMILES: O(C)C1=C(C=CC=C1)N2CCN(C(/C=C/C=C/C=3C=C4C(=CC3)OCO4)=O)CC2
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis