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HIV-IN-13 prodrug

SKU: orb3174551

Description

HIV-IN-13 prodrug (Compound 8) is a precursor to an HIV inhibitor. It shows no antiviral activity in the absence of glutathione (GSH). However, with the addition of 1 mM and 2 mM GSH, the EC50 values against HIV-1 are 10 μM and 8.2 μM, respectively. HIV-IN-13 prodrug is applicable for HIV infection research.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number3049284-12-7
MW677.64
FormulaC31H25F2N7O7S
SMILESO=C(NCC1=NC(=CC=C1)C)C2=CN(C3=CC=4OC(F)(F)OC4C=C3C2=O)CCNC(=O)C=5C=CC=CC5SC6=C(N=CN6C)N(=O)=O
TargetHIV Protease

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information