HIV-1 Rev (34-50)

SKU: orb1296733

Description

This 17-amino acid peptide corresponds to the Rev-responsive element (RRE)-binding domain (residues 34-50) of the HIV-1 Rev protein. It exhibits anti-HIV-1 activity and is widely used in vitro to study Rev-RRE interactions, viral replication mechanisms, and as a lead for inhibitor development.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 141237-50-5
• MW: 2437.74
• Purity: 99.91% (May vary between batches)
• Formula: C₉₇H₁₇₃N₅₁O₂₄
• SMILES: C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)C=1C=2C(NC1)=CC=CC2
• Target: HIV Protease

Bioactivity

• In Vitro:
  The 17-aa peptide HIV-1 Rev (34-50), derived from the Rev-responsive element (RRE)-binding domains of HIV-1 Rev, exhibits anti-HIV-1 activity.

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, HIV-1, HIV Protease, HIV 1 Rev (34 50), HIV-1 Rev, HIV1 Rev (3450), HIV-1 Rev 34-50, HIV-1 rev Protein, HIV-1 rev Protein (34-50), HIVProtease, HIV, Human immunodeficiency virus, inhibit

Compound Identifiers

PubChem CID

16141162