HIV-1 inhibitor-6

SKU: orb1297844

Description

HIV-1 inhibitor-6 is a small molecule that selectively inhibits HIV-1 pre-mRNA splicing, thereby blocking viral replication. It serves as a valuable research tool for studying HIV-1 gene expression and splicing mechanisms in vitro, offering insights for antiviral development.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 1821309-39-0
• MW: 330.32
• Purity: 99.33%
• Formula: C₁₄H₁₀N₄O₄S
• SMILES: Cn1ccc(=O)c(c1)C(=O)Nc1nsc2ccc(cc12)[N+]([O-])=O
• Target: HIV Protease
• Solubility: DMSO:3 mg/mL (9.08 mM)

Bioactivity

• Target IC50:
  R5 HIV-1:0.9 μM (EC50)|X4 HIV-1 (IIIB):0.6 μM (EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

coreceptor CCR5, Diheteroarylamide, 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-, 97USSN54, Inhibitor, inhibit, HIV-1IIIB, HIV-1 inhibitor-6, HIV1 inhibitor6 , HIV-1, HIV 1 inhibitor 6 , HIV, HIV Protease, HIVProtease, Human immunodeficiency virus, integrase, replication, reverse transcriptase, protease, R5-tropic, X4-tropic, pre-mRNA alternative splicing

Compound Identifiers

PubChem CID

92045028