Histatin 5 acetate

SKU: orb1296527

Description

Histatin 5 acetate is a potent inhibitor of the host gelatinases MMP-2 and MMP-9, exhibiting IC50 values of 0.57 µM and 0.25 µM, respectively. This synthetic peptide is a valuable research tool for studying extracellular matrix remodeling in contexts such as cancer metastasis, inflammation, and wound healing in both in vitro and ex vivo models.

Research Area

Protein Biochemistry

Key Properties

• Target: MMP
• MW: 3096.35
• Purity: 98.72% (May vary between batches)
• Formula: C₁₃₅H₁₉₉N₅₁O₃₅
• SMILES: OC([C@@H](NC(CNC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@@H](NC([C@@H](NC([C@H](CO)NC([C@@H](N)CC(O)=O)=O)=O)CC1=CN=CN1)=O)C)=O)=O)=O)CC2=CN=CN2)=O)CC3=CN=CN3)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)=O)CC5=CC=CC=C5)=O)CC6=CN=CN6)=O)=O)=O)CC7=CN=CN7)=O)CC8=CN=CN8)=O)=O)CC9=CN=CN9)=O)=O)=O)CC%10=CC=C(O)C=C%10)=O.CC(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

115966-68-2, 115966-68-2 Free base, MMP-9, MMP-2, Histatin 5 acetate, Histatin 5 Acetate, Histatin 5 acetate (115966-68-2 Free base)

Compound Identifiers

PubChem CID

163285785