HIF-1α-IN-2 hydrochloride

SKU: orb2278855

Description

HIF-1α-IN-2 hydrochloride is a potent, small molecule inhibitor of HIF-1α with demonstrated anticancer activity in vitro, showing IC50 values of 28 nM and 15 nM in MDA-MB-231 and MiaPaCa-2 cell lines, respectively. It functions by suppressing both the transcription and translation of HIF-1α, making it a valuable tool for researching hypoxia signaling pathways in cancer biology.

Research Area

Epigenetics & Chromatin, Metabolism Research

Key Properties

• MW: 397.92
• Formula: C₂₁H₂₀ClN₃OS
• Target: HIF/HIF Prolyl-Hydroxylase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HIF/HIF Prolyl-Hydroxylase