HIF-1 alpha (556-574)

SKU: orb1983985

Description

This 19-mer peptide fragment (HIF-1α 556-574) corresponds to the oxygen-dependent degradation domain critical for VHL recognition and proteasomal targeting. It serves as a key research tool for studying hypoxia signaling pathways, enabling in vitro binding assays and mechanistic investigations into oxygen-sensing and protein stability.

Research Area

Epigenetics & Chromatin, Metabolism Research

Key Properties

• Target: HIF/HIF Prolyl-Hydroxylase
• CAS Number: 1201633-99-9
• MW: 2254.6
• Formula: C₁₀₁H₁₅₀D₂N₂₀O₃₄S₂
• SMILES: C([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CC(C)C)=O)CC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCSC)=O)CC(C)C)=O)C)=O)C[C@@H]([C@@H]1[2H])[2H])CC2=CC=C(O)C=C2)=O)[C@H](CC)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCC(N)=O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)CCSC)=O)CCC3

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176418843