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HI5

SKU: orb1744051

Description

HI5 is a dual-action small molecule with potent antitumor activity, functioning as both a tubulin polymerization inhibitor and an indoleamine 2,3-dioxygenase (IDO) suppressor. It induces cell cycle arrest, apoptosis, and oxidative stress in vitro (IC50 = 70 nM in HeLa cells) and is a candidate for research in cancer immunology and metastasis.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2411548-90-6
MW745.82
FormulaC42H43N5O8
SMILESC(C(C(OCCC1=CN(CC2=CC(C(OC3=C(OC)C=CC(/C=C\C4=CC(OC)=C(OC)C(OC)=C4)=C3)=O)=CC=C2)N=N1)=O)N)C=5C=6C(N(C)C5)=CC=CC6
TargetIDO,Others,Microtubule Associated,Indoleamine 2,3-Dioxygenase (IDO),Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information