HG-7-85-01-NH2

SKU: orb2300273

Description

SNIPER(ABL)-033 is a heterobifunctional degrader that links the ABL inhibitor HG-7-85-01 to an IAP ligand, inducing targeted degradation of BCR-ABL with a DC50 of 0.3 µM. It serves as a research tool for studying targeted protein degradation in oncology, applicable in both cellular and in vivo models of BCR-ABL-driven cancers.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1258391-29-5
• MW: 540.6
• Formula: C₂₇H₂₇F₃N₆OS
• SMILES: C(C1=C(C(F)(F)F)C=C(NC(=O)C2=CC(=CC=C2)C=3N=C4C(=CC3)N=C(N)S4)C=C1)N5CCN(CC)CC5
• Target: PROTACs,Others,SNIPERs,Ligands for Target Protein for PROTAC,Bcr-Abl

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

49839810